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eribulin mesilate

CMI, dosage, igredients, prescription medications, price, photo

What HALAVEN is used for

HALAVEN contains the active ingredient eribulin mesilate.

Halaven belongs to a group of medicines called Anti-cancer agents. It works by stopping the growth and spread of cancer cells.

HALAVEN is used for the treatment of breast cancer. It is used when at least two other therapies for locally advanced or metastatic breast cancer (i.e.; breast cancer that has spread beyond the original tumour) have been tried but have lost their effect.

Before you take HALAVEN

When you must not take it

Do not use HALAVEN:

  • If you are allergic (hypersensitive) to eribulin mesilate or any of the other ingredients of HALAVEN. Some of the symptoms of an allergic reaction may include:
    - Shortness of breath
    - Wheezing or difficulty in breathing
    - Swelling of the face, lips, tongue or other parts of the body
    - Rash, itching, hives on the skin
  • If you are breast feeding

Take special care with HALAVEN:

  • If you have liver problems
  • If you have a fever or an infection
    If you experience numbness, tingling, prickling sensations, sensitivity to touch or muscle weakness
  • If you have heart problems

If any of these affects you, tell your doctor who may wish to stop treatment or reduce the dose.

Taking other medicines

Tell your doctor if you are taking any other medicines, including any that you buy without a prescription from your pharmacy, supermarket or health food shop.

Please tell your doctor, if you are taking or have recently taken any other medicines, including herbal supplements and medicines obtained without a prescription.

Pregnancy and breast feeding
HALAVEN may cause serious birth defects and should not be used if you are pregnant unless it is thought clearly necessary after carefully considering all the risks to you and the baby. It may also cause future fertility problems in men if they take it and they should discuss this with their doctor before starting treatment.

Women of childbearing age should use effective contraception during and up to 3 months after treatment with HALAVEN.

HALAVEN should not be used during breast feeding because of the possibility of risk to the child.

Important information about some of the ingredients of HALAVEN
This medicinal product contains small amounts if ethanol (alcohol), less than 100mg in an average dose.

Your doctor and pharmacist have more information on medicines to be careful with or avoid while taking this medicine.

How Halaven is given

HALAVEN will be given to you by a doctor or nurse as an injection into a vein, over a period of 2-5 minutes. The dose you will receive is based on your body surface area (expressed in squared metres, or m2) which is calculated from your weight and height. The usual dose of HALAVEN is 1.4mg/m2, but this may be adjusted by your doctor based on your blood test results or other factors.

How often will you be given HALAVEN

HALAVEN is usually given on Days 1 and 8 of every 21-day cycle. Your doctor will determine how many cycles of treatment you should receive.

If you have any further questions about the use of this product, ask your doctor.

While you are taking HALAVEN

Things you must do

Tell any other doctors, dentists and pharmacists who treat you that you are taking this medicine.

If you become pregnant while taking HALAVEN, tell your doctor immediately.

Things you must not do

Do not take any other medicines, whether they require a prescription or not, without first telling your doctor or consulting with a pharmacist.

Things to be careful of

Be careful driving or operating machinery until you know how HALAVEN affects you.

HALAVEN may cause side effects such as tiredness (very common) and dizziness (common).

Do not drive or use machinery if you feel tired or dizzy.

Side effects

All medicines may have some unwanted side effects. Sometimes they are serious, but most of the time they are not. Your doctor has weighed the risks of using this medicine against the benefits he/she expects it will have for you.

Do not be alarmed by the following list of side effects. You may not experience any of them.

Ask your doctor or pharmacist answer any questions you may have.

Tell your doctor or pharmacist if you notice any of the following and they worry you:

  • Decrease in the number of white blood cells or red blood cells
  • Nausea, vomiting, constipation, diarrhoea
  • Tiredness or weakness
  • Fever
  • Loss of appetite
  • Pain in the joints and muscles
  • Numbness, tingling or prickling sensations
  • Headache
  • Muscle pain
  • Hair loss

The above list includes the very common side effects of your medicine.

Tell your doctor as soon as possible if you notice and if the following:

  • Decrease in the number of platelets
  • Infection with fever, chills
  • Fast heart rate, flushing
  • Vertigo, dizziness
  • Increased production of tears, conjunctivitis, nose bleeds
  • Dehydration, dry mouth, mouth ulcers, oral thrush, indigestion, heartburn, abdominal pain or swelling
  • Swelling of soft tissues, pains, (in particular chest, back and bone pain), muscle spasm or weakness
  • Mouth, respiratory and urinary tract infections. Sore throat, red, sore or runny nose, flu-like symptoms
  • Liver function test abnormalities, altered level of sugar, phosphates, potassium or magnesium in the blood
  • Weight loss
  • Inability to sleep, depression, changed sense of taste
  • Difficulty breathing, cough, throat pain
  • Rash, itching, swelling and numbness of the hand and feet nail problems, dry or red skin
  • Excessive sweating (including night sweats)

The above list contains common side effects.

Tell your doctor as soon as possible if you notice any of the following:

  • Severe infection with blood poisoning (sepsis), cold sores, shingles
  • Ring in the ear
  • Blood clots
  • Pneumonia
  • High levels of bilirubin in the blood
  • Local swelling of the skin
  • Kidney failure, blood or protein in the urine, painful urination

The above list contains uncommon side effects.

Tell your doctor or pharmacist if you notice anything that is making you feel unwell. Other side effects not listed above may also occur in some people.

After taking HALAVEN


Keep out of the reach and sight of children.

Do not use HALAVEN after the expiry date which is stated on the carton and the vial after EXP: The expiry date refers to the last day of the month.

Unopened vials will be stored below 25°C.

Product description

What it looks like

HALAVEN is a clear, colourless aqueous solution for injection available in glass vials containing 2mL of solution (0.5mg/mL).


Active ingredient(s):

  • Eribulin Mesilate

Inactive ingredients (tablets):

  • Ethanol
  • Water for injections

Note: This information may not be actual at the time of reading. Always look for actual instructions in the package with the medication.
It is forbidden to use these materials without the advice of healthcare professional.

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